Description
Product Characteristics:
Aliases: b R1 antibody, b-R1 antibody, Beta-R1 antibody, betaR1 antibody, C-X-C motif chemokine 11 antibody, Chemokine (C-X-C motif) ligand 11 antibody, Chemokine C-X-C motif ligand 11 antibody, CXC11 antibody, CXCL11 antibody, CXL11_HUMAN antibody, H174 antibody, I TAC antibody, I-TAC antibody, Interferon gamma inducible protein 9 antibody, Interferon gamma-inducible protein 9 antibody, Interferon inducible T cell alpha chemoattractant antibody, Interferon-inducible T-cell a chemoattractant I-TAC antibody, Interferon-inducible T-cell alpha chemoattractant antibody, IP 9 antibody, IP-9 antibody, IP9 antibody, ITAC antibody, MGC102770 antibody, SCYB11 antibody, SCYB9B antibody, Small inducible cytokine B11 antibody, Small inducible cytokine subfamily B (Cys-X-Cys) member 11 antibody, Small inducible cytokine subfamily B (Cys-X-Cys) member 9B antibody, Small inducible cytokine subfamily B, member 11 antibody, Small inducible cytokine subfamily B, member 9B antibody, Small-inducible cytokine B11 antibody
Target Information: Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. [provided by RefSeq, Jul 2008]